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Samantha Who?
Samantha Newly has been a bad, bad girl. But thanks to an 8-day coma, she can't remember a thing. Fortunately her best friend Andrea is by her side with a cocktail and the 4-1-1 on every dirty deed. But the more Sam pieces together her past, the less she likes her old self. Maybe this is a chance to start over and do it all again.
Last Episode Date: 2009-07-23
Comedy
★★★★★★★★★★ (75 votes)
Official website: https://abc.com/shows/samantha-who
Casts
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Christina Applegate
as Samantha Newly
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Jennifer Esposito
as Andrea Belladonna
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Kevin Dunn
as Howard
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Melissa McCarthy
as Dena
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Tim Russ
as Frank
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Barry Watson
as Todd
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Jean Smart
as Regina Newly